Thank you, Sue! I passed it along. Best, Cary -----Original Message----- From: Sue Klemmer <Sue_Klemmer@xxxxxxxxxxxxx> To: neact <neact@xxxxxxxxxxxxx> Sent: Thu, Feb 7, 2013 5:24 pm Subject: [neact] Re: Fwd: [Nhsci-ed] Nhsci-ed Digest, Vol 121, Issue 13 neact@xxxxxxxxxxxxx writes: Hello All, Does anyone know what the suffix -orphin means? (Exorphins, endorphins...) I "Googled" it and was unsuccessful in my search. Cary - endorphin (n.) 1975, from French endorphine, from endogène "endogenous, growing within" (see endo- + genus) + (mo)rphine. Looks like -"orphin" did not have a specific chemical meaning as a suffix, but instead started with the word "endorphin" and then was modifed from there to fit other similar compounds like exorphins. According to Wikipedia "Endorphins ("endogenous morphine") are endogenous opioid peptides that function as neurotransmitters.[1] ". So the "-rphine" ending refers to the opiate qualities of endorphins. You might find more if you looked at the history of the discovery of endorphins. I don't know enough biochemistry to help you out any further. Sue Klemmer