Hi there. I use the Native instruments Vocator. its a wonderful plugin for vocal effects. though I also love to use my Roland V-Synth for the work. Sync issues are normally the result of using that plugin with a card where latencies don't match up and you get issues. best thing is to set up your card for the lowest possible latencies, then start using your audio processors, audio metranome and your vst instruments etc for it. then you'll find a tighter interface. I haven't had many problems there since using a rather interesting interface from digidesign . (control 24) by the way great mixer interface, accessible and runs well with sonar. though the price is a bit stupid. lew